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, now in its fifth edition, offers medical students all they need to know to become safe and effective prescribers. It forms a complete, integrated resource for basic pharmaceutical science, pathophysiology, clinical pharmacology, and therapeutics. The fifth edition has been extensively revised and updated throughout. Key features include: Clear, disease-based approach. Presentation of how drugs are used in clinical practice. Succinct explanations of the major pathogenic mechanisms of each disease and consequent clinical signs and symptoms. Comprehensive reviews of major drug classes relevant to each disease. Structured approach to the principles of disease management – outlining core principles of drug choice and planning a therapeutic regimen for common diseases. Quick-reference drug compendia illustrating key similarities and differences among all BNF-listed drugs in each class. Comes with free e-book on StudentConsult. New sections on key and evolving topics, including prescribing safety and pharmacovigilance. Updated figures to further clarify complex areas. Over 800 revised multiple-choice and case-based questions for self-assessment.